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Inhibition of the MEK1/ERK pathway reduces arachidonic acid release independently of cPLA(2) phosphorylation and translocation
BACKGROUND: The 85-kDa cytosolic phospholipase A(2) (cPLA(2)) mediates arachidonic acid (AA) release in MDCK cells. Although calcium and mitogen-activated protein kinases regulate cPLA(2), the correlation of cPLA(2) translocation and phosphorylation with MAPK activation and AA release is unclear. RE...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC130032/ https://ncbi.nlm.nih.gov/pubmed/12370087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-3-30 |
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