Association of MHC and rheumatoid arthritis: Association of RA with HLA-DR4 - the role of repertoire selection
Most patients with rheumatoid arthritis (RA) express HLA-DR4, HLA-DR1 or HLA-DR10. These alleles share a common amino acid motif in their third hypervariable regions: the shared epitope. In normals and patients with RA, HLA-DR genes exert a major influence on the CD4 αβ T-cell repertoire, as shown b...
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| Publicat a: | Arthritis Res |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC130006/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11094433/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/ar91 |
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