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Single molecule analysis of RNA polymerase elongation reveals uniform kinetic behavior
By using single-molecule measurements, we demonstrate that the elongation kinetics of individual Escherichia coli RNA polymerase molecules are remarkably homogeneous. We find no evidence of distinct elongation states among RNA polymerases. Instead, the observed heterogeneity in transcription rates r...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The National Academy of Sciences
2002
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129709/ https://ncbi.nlm.nih.gov/pubmed/12370445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212358999 |
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