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Hierarchical, clustered protein interactions with U4/U6 snRNA: a biochemical role for U4/U6 proteins

During activation of the spliceosome, the U4/U6 snRNA duplex is dissociated, releasing U6 for subsequent base pairing with U2 snRNA. Proteins that directly bind the U4/U6 interaction domain potentially could mediate these structural changes. We thus investigated binding of the human U4/U6-specific p...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO J
Egile Nagusiak: Nottrott, Stephanie, Urlaub, Henning, Lührmann, Reinhard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129076/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12374753/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf544
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