Hierarchical, clustered protein interactions with U4/U6 snRNA: a biochemical role for U4/U6 proteins
During activation of the spliceosome, the U4/U6 snRNA duplex is dissociated, releasing U6 for subsequent base pairing with U2 snRNA. Proteins that directly bind the U4/U6 interaction domain potentially could mediate these structural changes. We thus investigated binding of the human U4/U6-specific p...
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| Udgivet i: | EMBO J |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129076/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12374753/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf544 |
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