Hierarchical, clustered protein interactions with U4/U6 snRNA: a biochemical role for U4/U6 proteins

During activation of the spliceosome, the U4/U6 snRNA duplex is dissociated, releasing U6 for subsequent base pairing with U2 snRNA. Proteins that directly bind the U4/U6 interaction domain potentially could mediate these structural changes. We thus investigated binding of the human U4/U6-specific p...

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Pubblicato in:	EMBO J
Autori principali:	Nottrott, Stephanie, Urlaub, Henning, Lührmann, Reinhard
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2002
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129076/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12374753/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf544
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