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Synergistic inhibition of human melanoma proliferation by combination treatment with B-Raf inhibitor BAY43-9006 and mTOR inhibitor Rapamycin

BACKGROUND: Targeted inhibition of protein kinases is now acknowledged as an effective approach for cancer therapy. However, targeted therapies probably have limited success because cancer cells have alternate pathways for survival and proliferation thereby avoiding inhibition. We tested the hypothe...

詳細記述

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書誌詳細
主要な著者: Molhoek, Kerrington R, Brautigan, David L, Slingluff, Craig L
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1289294/
https://ncbi.nlm.nih.gov/pubmed/16255777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-3-39
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