The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation

Recurrent genetic alterations in human medulloblastoma (MB) include mutations in the sonic hedgehog (SHH) signaling pathway and TP53 inactivation (∼25% and 10% of cases, respectively). However, mouse models of MB, regardless of their initiating lesions, generally depend upon p53 inactivation for rap...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Uziel, Tamar, Zindy, Frederique, Xie, Suqing, Lee, Youngsoo, Forget, Antoine, Magdaleno, Susan, Rehg, Jerold E., Calabrese, Christopher, Solecki, David, Eberhart, Charles G., Sherr, Sarah E., Plimmer, Sarah, Clifford, Steven C., Hatten, Mary E., McKinnon, Peter J., Gilbertson, Richard J., Curran, Tom, Sherr, Charles J., Roussel, Martine F.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283959/
https://ncbi.nlm.nih.gov/pubmed/16260494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1368605
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados