Timp3 deficiency in insulin receptor–haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-α

Activation of inflammatory pathways may contribute to the beginning and the progression of both atherosclerosis and type 2 diabetes. Here we report a novel interaction between insulin action and control of inflammation, resulting in glucose intolerance and vascular inflammation and amenable to thera...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Federici, Massimo, Hribal, Marta L., Menghini, Rossella, Kanno, Hiroko, Marchetti, Valentina, Porzio, Ottavia, Sunnarborg, Susan W., Rizza, Stefano, Serino, Matteo, Cunsolo, Veronica, Lauro, Davide, Mauriello, Alessandro, Smookler, David S., Sbraccia, Paolo, Sesti, Giorgio, Lee, David C., Khokha, Rama, Accili, Domenico, Lauro, Renato
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2005
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283942/
https://ncbi.nlm.nih.gov/pubmed/16294222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26052
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