Decreased IRS2 and TIMP3 Expression in Monocytes From Offspring of Type 2 Diabetic Patients Is Correlated With Insulin Resistance and Increased Intima-Media Thickness

OBJECTIVE: In humans, it is unclear if insulin resistance at the monocyte level is associated with atherosclerosis in vivo. Here we have studied first-degree relatives of patients with type 2 diabetes to investigate whether a reduction in components of the insulin signal transduction pathways, such...

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Detalhes bibliográficos
Main Authors: Cardellini, Marina, Menghini, Rossella, Luzi, Alessio, Davato, Francesca, Cardolini, Iris, D'Alfonso, Rossella, Gentileschi, Paolo, Rizza, Stefano, Marini, Maria Adelaide, Porzio, Ottavia, Lauro, Davide, Sbraccia, Paolo, Lauro, Renato, Federici, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Complications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219931/
https://ncbi.nlm.nih.gov/pubmed/21984580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0162
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