TIMP3 Is Reduced in Atherosclerotic Plaques From Subjects With Type 2 Diabetes and Increased by SirT1

OBJECTIVE: Atherosclerosis is accelerated in subjects with type 2 diabetes by unknown mechanisms. We identified tissue inhibitor of metalloproteinase 3 (TIMP3), the endogenous inhibitor of A disintegrin and metalloprotease domain 17 (ADAM17) and other matrix metalloproteinases (MMPs), as a gene modi...

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Detalhes bibliográficos
Main Authors: Cardellini, Marina, Menghini, Rossella, Martelli, Eugenio, Casagrande, Viviana, Marino, Arianna, Rizza, Stefano, Porzio, Ottavia, Mauriello, Alessandro, Solini, Anna, Ippoliti, Arnaldo, Lauro, Renato, Folli, Franco, Federici, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750223/
https://ncbi.nlm.nih.gov/pubmed/19581416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0280
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