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Restoration of renal TIMP3 levels via genetics and pharmacological approach prevents experimental diabetic nephropathy
BACKGROUND: Diabetic nephropathy (DN), one of the major complications of diabetes, is characterized by albuminuria, glomerulosclerosis, and progressive loss of renal function. Loss of TIMP3, an Extracellular Matrix bound protein affecting both inflammation and fibrosis, is a hallmark of DN in human...
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| Gepubliceerd in: | Clin Transl Med |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2021
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7862169/ https://ncbi.nlm.nih.gov/pubmed/33634991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.305 |
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