Restoration of renal TIMP3 levels via genetics and pharmacological approach prevents experimental diabetic nephropathy

BACKGROUND: Diabetic nephropathy (DN), one of the major complications of diabetes, is characterized by albuminuria, glomerulosclerosis, and progressive loss of renal function. Loss of TIMP3, an Extracellular Matrix bound protein affecting both inflammation and fibrosis, is a hallmark of DN in human...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Clin Transl Med
Hlavní autoři: Casagrande, Viviana, Iuliani, Giulia, Menini, Stefano, Pugliese, Giuseppe, Federici, Massimo, Menghini, Rossella
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862169/
https://ncbi.nlm.nih.gov/pubmed/33634991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.305
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky