Role of peroxisome proliferator-activated receptor γ in amyloid precursor protein processing and amyloid β-mediated cell death

Recent data indicate that PPARγ (peroxisome proliferator-activated receptor γ) could be involved in the modulation of the amyloid cascade causing Alzheimer's disease. In the present study we show that PPARγ overexpression in cultured cells dramatically reduced Aβ (amyloid-β) secretion, affectin...

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Hlavní autoři: d'Abramo, Cristina, Massone, Sara, Zingg, Jean-Marc, Pizzuti, Antonio, Marambaud, Philippe, Dalla Piccola, Bruno, Azzi, Angelo, Marinari, Umberto M., Pronzato, Maria A., Ricciarelli, Roberta
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2005
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276971/
https://ncbi.nlm.nih.gov/pubmed/15946122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050560
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