Role of peroxisome proliferator-activated receptor γ in amyloid precursor protein processing and amyloid β-mediated cell death

Recent data indicate that PPARγ (peroxisome proliferator-activated receptor γ) could be involved in the modulation of the amyloid cascade causing Alzheimer's disease. In the present study we show that PPARγ overexpression in cultured cells dramatically reduced Aβ (amyloid-β) secretion, affectin...

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Detalhes bibliográficos
Main Authors: d'Abramo, Cristina, Massone, Sara, Zingg, Jean-Marc, Pizzuti, Antonio, Marambaud, Philippe, Dalla Piccola, Bruno, Azzi, Angelo, Marinari, Umberto M., Pronzato, Maria A., Ricciarelli, Roberta
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276971/
https://ncbi.nlm.nih.gov/pubmed/15946122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050560
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