Role of peroxisome proliferator-activated receptor γ in amyloid precursor protein processing and amyloid β-mediated cell death

Recent data indicate that PPARγ (peroxisome proliferator-activated receptor γ) could be involved in the modulation of the amyloid cascade causing Alzheimer's disease. In the present study we show that PPARγ overexpression in cultured cells dramatically reduced Aβ (amyloid-β) secretion, affectin...

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Main Authors: d'Abramo, Cristina, Massone, Sara, Zingg, Jean-Marc, Pizzuti, Antonio, Marambaud, Philippe, Dalla Piccola, Bruno, Azzi, Angelo, Marinari, Umberto M., Pronzato, Maria A., Ricciarelli, Roberta
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2005
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276971/
https://ncbi.nlm.nih.gov/pubmed/15946122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050560
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