Peroxisome Proliferator-Activated Receptor γ Induces a Clearance Mechanism for the Amyloid-β Peptide

We investigated whether peroxisome proliferator-activated receptor γ (PPARγ) could be involved in the modulation of the amyloid cascade causing Alzheimer's disease. Inducing expression or activating PPARγ using synthetic agonists of the thiazolinedione family results in a dramatic decrease in t...

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Vydáno v:J Neurosci
Hlavní autoři: Camacho, Ira Espuny, Serneels, Lutgarde, Spittaels, Kurt, Merchiers, Pascal, Dominguez, Diana, De Strooper, Bart
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2004
Témata:
Neurobiology of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730204/
https://ncbi.nlm.nih.gov/pubmed/15574741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3987-04.2004
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