Peroxisome Proliferator-Activated Receptor γ Induces a Clearance Mechanism for the Amyloid-β Peptide

We investigated whether peroxisome proliferator-activated receptor γ (PPARγ) could be involved in the modulation of the amyloid cascade causing Alzheimer's disease. Inducing expression or activating PPARγ using synthetic agonists of the thiazolinedione family results in a dramatic decrease in t...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Camacho, Ira Espuny, Serneels, Lutgarde, Spittaels, Kurt, Merchiers, Pascal, Dominguez, Diana, De Strooper, Bart
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730204/
https://ncbi.nlm.nih.gov/pubmed/15574741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3987-04.2004
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