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A colorimetric method for point mutation detection using high-fidelity DNA ligase

The present study reported proof-of-principle for a genotyping assay approach that can detect single nucleotide polymorphisms (SNPs) through the gold nanoparticle assembly and the ligase reaction. By incorporating the high-fidelity DNA ligase (Tth DNA ligase) into the allele-specific ligation-based...

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Detalhes bibliográficos
Main Authors: Li, Jishan, Chu, Xia, Liu, Yali, Jiang, Jian-Hui, He, Zhimin, Zhang, Zhiwei, Shen, Guoli, Yu, Ru-Qin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1275593/
https://ncbi.nlm.nih.gov/pubmed/16257979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni163
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