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Efficiency and fidelity of T3 DNA ligase in ligase-catalysed oligonucleotide polymerisations
Ligase-catalyzed oligonucleotide polymerisations (LOOPER) can readily generate libraries of diversely-modified nucleic acid polymers, which can be subjected to iterative rounds of in vitro selection to evolve functional activity. While there exist several different DNA ligases, T4 DNA ligase has mos...
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| Udgivet i: | Org Biomol Chem |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6374181/ https://ncbi.nlm.nih.gov/pubmed/30357247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob01958d |
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