Single- and Multiple-Dose Pharmacokinetics of Caspofungin in Healthy Men

Caspofungin, a glucan synthesis inhibitor, is being developed as a parenteral antifungal agent. The pharmacokinetics of caspofungin following 1-h intravenous infusions in healthy men was investigated in four phase I studies. In an alternating two-panel (six men each), rising-single-dose study, plasm...

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Εκδόθηκε σε:	Antimicrob Agents Chemother
Κύριοι συγγραφείς:	Stone, Julie A., Holland, Sherry D., Wickersham, Peter J., Sterrett, Andrew, Schwartz, Michael, Bonfiglio, Cynthia, Hesney, Michael, Winchell, Gregory A., Deutsch, Paul J., Greenberg, Howard, Hunt, Thomas L., Waldman, Scott A.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 2002
Θέματα:	Pharmacology
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127465/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850256/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.3.739-745.2002
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