Single- and Multiple-Dose Pharmacokinetics of Caspofungin in Healthy Men

Caspofungin, a glucan synthesis inhibitor, is being developed as a parenteral antifungal agent. The pharmacokinetics of caspofungin following 1-h intravenous infusions in healthy men was investigated in four phase I studies. In an alternating two-panel (six men each), rising-single-dose study, plasm...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Stone, Julie A., Holland, Sherry D., Wickersham, Peter J., Sterrett, Andrew, Schwartz, Michael, Bonfiglio, Cynthia, Hesney, Michael, Winchell, Gregory A., Deutsch, Paul J., Greenberg, Howard, Hunt, Thomas L., Waldman, Scott A.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2002
Témata:	Pharmacology
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127465/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850256/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.3.739-745.2002
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