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Single- and Multiple-Dose Pharmacokinetics of Caspofungin in Healthy Men

Caspofungin, a glucan synthesis inhibitor, is being developed as a parenteral antifungal agent. The pharmacokinetics of caspofungin following 1-h intravenous infusions in healthy men was investigated in four phase I studies. In an alternating two-panel (six men each), rising-single-dose study, plasm...

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Kaydedildi:
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Stone, Julie A., Holland, Sherry D., Wickersham, Peter J., Sterrett, Andrew, Schwartz, Michael, Bonfiglio, Cynthia, Hesney, Michael, Winchell, Gregory A., Deutsch, Paul J., Greenberg, Howard, Hunt, Thomas L., Waldman, Scott A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2002
Konular:
Pharmacology
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127465/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850256/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.3.739-745.2002
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