Single- and Multiple-Dose Pharmacokinetics of Caspofungin in Healthy Men

Caspofungin, a glucan synthesis inhibitor, is being developed as a parenteral antifungal agent. The pharmacokinetics of caspofungin following 1-h intravenous infusions in healthy men was investigated in four phase I studies. In an alternating two-panel (six men each), rising-single-dose study, plasm...

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Detalhes bibliográficos
Main Authors: Stone, Julie A., Holland, Sherry D., Wickersham, Peter J., Sterrett, Andrew, Schwartz, Michael, Bonfiglio, Cynthia, Hesney, Michael, Winchell, Gregory A., Deutsch, Paul J., Greenberg, Howard, Hunt, Thomas L., Waldman, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127465/
https://ncbi.nlm.nih.gov/pubmed/11850256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.3.739-745.2002
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