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Single- and Multiple-Dose Pharmacokinetics of Caspofungin in Healthy Men

Caspofungin, a glucan synthesis inhibitor, is being developed as a parenteral antifungal agent. The pharmacokinetics of caspofungin following 1-h intravenous infusions in healthy men was investigated in four phase I studies. In an alternating two-panel (six men each), rising-single-dose study, plasm...

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Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Stone, Julie A., Holland, Sherry D., Wickersham, Peter J., Sterrett, Andrew, Schwartz, Michael, Bonfiglio, Cynthia, Hesney, Michael, Winchell, Gregory A., Deutsch, Paul J., Greenberg, Howard, Hunt, Thomas L., Waldman, Scott A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2002
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127465/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850256/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.3.739-745.2002
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