Potent and Selective Inhibition of Human Cytomegalovirus Replication by 1263W94, a Benzimidazole l-Riboside with a Unique Mode of Action

Benzimidazole nucleosides have been shown to be potent inhibitors of human cytomegalovirus (HCMV) replication in vitro. As part of the exploration of structure-activity relationships within this series, we synthesized the 2-isopropylamino derivative (3322W93) of 1H-β-d-ribofuranoside-2-bromo-5,6-dic...

Popoln opis

Bibliografske podrobnosti

izdano v:	Antimicrob Agents Chemother
Principais autores:	Biron, Karen K., Harvey, Robert J., Chamberlain, Stanley C., Good, Steven S., Smith III, Albert A., Davis, Michelle G., Talarico, Christine L., Miller, Wayne H., Ferris, Robert, Dornsife, Ronna E., Stanat, Sylvia C., Drach, John C., Townsend, Leroy B., Koszalka, George W.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2002
Teme:	Antiviral Agents
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127361/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12121906/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.8.2365-2372.2002
Oznake:	Označite Brez oznak, prvi označite!