Potent and Selective Inhibition of Human Cytomegalovirus Replication by 1263W94, a Benzimidazole l-Riboside with a Unique Mode of Action

Benzimidazole nucleosides have been shown to be potent inhibitors of human cytomegalovirus (HCMV) replication in vitro. As part of the exploration of structure-activity relationships within this series, we synthesized the 2-isopropylamino derivative (3322W93) of 1H-β-d-ribofuranoside-2-bromo-5,6-dic...

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Библиографические подробности
Главные авторы: Biron, Karen K., Harvey, Robert J., Chamberlain, Stanley C., Good, Steven S., Smith III, Albert A., Davis, Michelle G., Talarico, Christine L., Miller, Wayne H., Ferris, Robert, Dornsife, Ronna E., Stanat, Sylvia C., Drach, John C., Townsend, Leroy B., Koszalka, George W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2002
Предметы:
Antiviral Agents
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC127361/
https://ncbi.nlm.nih.gov/pubmed/12121906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2365-2372.2002
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