ATP-Dependent Removal of Nucleoside Reverse Transcriptase Inhibitors by Human Immunodeficiency Virus Type 1 Reverse Transcriptase

Removal of nucleoside chain terminator inhibitors mediated by human immunodeficiency virus (HIV) reverse transcriptase (RT) using ATP as an acceptor molecule has been proposed as a novel mechanism of HIV resistance. Recombinant wild-type and mutant HIV type 1 (HIV-1) RT enzymes with thymidine analog...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Naeger, Lisa K., Margot, Nicolas A., Miller, Michael D.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127313/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12069972/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.7.2179-2184.2002
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