Inhibitory Activities of Quinolones against DNA Gyrase and Topoisomerase IV of Enterococcus faecalis

We have cloned the DNA gyrase and topoisomerase IV genes of Enterococcus faecalis to examine the actions of quinolones against E. faecalis genetically and enzymatically. We first generated levofloxacin-resistant mutants of E. faecalis by stepwise selection with increasing drug concentrations and ana...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Onodera, Yoshikuni, Okuda, Jun, Tanaka, Mayumi, Sato, Kenichi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2002
Témata:	Mechanisms of Resistance
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127212/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019093/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.6.1800-1804.2002
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