Inhibitory Activities of Quinolones against DNA Gyrase and Topoisomerase IV of Enterococcus faecalis

We have cloned the DNA gyrase and topoisomerase IV genes of Enterococcus faecalis to examine the actions of quinolones against E. faecalis genetically and enzymatically. We first generated levofloxacin-resistant mutants of E. faecalis by stepwise selection with increasing drug concentrations and ana...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Onodera, Yoshikuni, Okuda, Jun, Tanaka, Mayumi, Sato, Kenichi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127212/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019093/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.6.1800-1804.2002
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