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Inhibitory Activities of Quinolones against DNA Gyrase and Topoisomerase IV of Enterococcus faecalis

We have cloned the DNA gyrase and topoisomerase IV genes of Enterococcus faecalis to examine the actions of quinolones against E. faecalis genetically and enzymatically. We first generated levofloxacin-resistant mutants of E. faecalis by stepwise selection with increasing drug concentrations and ana...

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Bibliographische Detailangaben
Hauptverfasser: Onodera, Yoshikuni, Okuda, Jun, Tanaka, Mayumi, Sato, Kenichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC127212/
https://ncbi.nlm.nih.gov/pubmed/12019093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.6.1800-1804.2002
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