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Inhibitory Activities of Quinolones against DNA Gyrase and Topoisomerase IV of Enterococcus faecalis

We have cloned the DNA gyrase and topoisomerase IV genes of Enterococcus faecalis to examine the actions of quinolones against E. faecalis genetically and enzymatically. We first generated levofloxacin-resistant mutants of E. faecalis by stepwise selection with increasing drug concentrations and ana...

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書誌詳細
主要な著者: Onodera, Yoshikuni, Okuda, Jun, Tanaka, Mayumi, Sato, Kenichi
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC127212/
https://ncbi.nlm.nih.gov/pubmed/12019093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.6.1800-1804.2002
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