Inhibitory Activities of Quinolones against DNA Gyrase and Topoisomerase IV of Enterococcus faecalis

We have cloned the DNA gyrase and topoisomerase IV genes of Enterococcus faecalis to examine the actions of quinolones against E. faecalis genetically and enzymatically. We first generated levofloxacin-resistant mutants of E. faecalis by stepwise selection with increasing drug concentrations and ana...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Onodera, Yoshikuni, Okuda, Jun, Tanaka, Mayumi, Sato, Kenichi
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Mechanisms of Resistance
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127212/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019093/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.6.1800-1804.2002
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