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Stability of New Carbapenem DA-1131 to Renal Dipeptidase (Dehydropeptidase I)
The stability of DA-1131 to renal dipeptidase (RDPase) (EC 3.4.13.19) was compared with that of imipenem and meropenem by V(max)/K(m) ratios as an index of the enzyme's preference for substrates. Our results showed a decreasing order of imipenem (6.24), meropenem (2.41), and DA-1131 (1.39). The...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC127065/ https://ncbi.nlm.nih.gov/pubmed/11796382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.2.575-577.2002 |
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