In Vivo Activity and Pharmacokinetic Evaluation of a Novel Long-Acting Carbapenem Antibiotic, MK-826 (L-749,345)

MK-826 (formerly L-749,345), is a potent 1-β-methyl carbapenem with a long half-life and broad spectrum of activity. This compound is presently in phase-II clinical trials. Its activity against a number of gram-positive and gram-negative organisms was compared to those of imipenem (IPM) and eight ot...

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Detalhes bibliográficos
Main Authors: Gill, Charles J., Jackson, Jesse J., Gerckens, Lynn S., Pelak, Barbara A., Thompson, Randall K., Sundelof, Jon G., Kropp, Helmut, Rosen, H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105722/
https://ncbi.nlm.nih.gov/pubmed/9687396
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