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MK0787 (N-formimidoyl thienamycin): evaluation of in vitro and in vivo activities.
The practical application of thienamycin, a novel beta-lactam antibiotic with a broad activity spectrum, was compromised by problems of instability. MK0787, N-formimidoyl thienamycin, does not have this liability. As reported, bacterial species resistant to most beta-lactam antibiotics, such as Pseu...
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| Опубликовано в: : | Antimicrob Agents Chemother |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
1980
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283917/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6931549/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.6.993 |
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