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MK0787 (N-formimidoyl thienamycin): evaluation of in vitro and in vivo activities.

The practical application of thienamycin, a novel beta-lactam antibiotic with a broad activity spectrum, was compromised by problems of instability. MK0787, N-formimidoyl thienamycin, does not have this liability. As reported, bacterial species resistant to most beta-lactam antibiotics, such as Pseu...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Kropp, H, Sundelof, J G, Kahan, J S, Kahan, F M, Birnbaum, J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1980
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283917/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6931549/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.6.993
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