MK0787 (N-formimidoyl thienamycin): evaluation of in vitro and in vivo activities.

The practical application of thienamycin, a novel beta-lactam antibiotic with a broad activity spectrum, was compromised by problems of instability. MK0787, N-formimidoyl thienamycin, does not have this liability. As reported, bacterial species resistant to most beta-lactam antibiotics, such as Pseu...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Kropp, H, Sundelof, J G, Kahan, J S, Kahan, F M, Birnbaum, J
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1980
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283917/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6931549/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.6.993
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