Antifungal Efficacy of Caspofungin (MK-0991) in Experimental Pulmonary Aspergillosis in Persistently Neutropenic Rabbits: Pharmacokinetics, Drug Disposition, and Relationship to Galactomannan Antigenemia

The antifungal efficacy, pharmacokinetics, and safety of caspofungin (CAS) were investigated in the treatment and prophylaxis of invasive pulmonary aspergillosis due to Aspergillus fumigatus in persistently neutropenic rabbits. Antifungal therapy consisted of 1, 3, or 6 mg of CAS/kg of body weight/d...

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Εκδόθηκε σε:	Antimicrob Agents Chemother
Κύριοι συγγραφείς:	Petraitiene, Ruta, Petraitis, Vidmantas, Groll, Andreas H., Sein, Tin, Schaufele, Robert L., Francesconi, Andrea, Bacher, John, Avila, Nilo A., Walsh, Thomas J.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 2002
Θέματα:	Experimental Therapeutics
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127008/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11751105/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.1.12-23.2002
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