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Process and Metabolic Strategies for Improved Production of Escherichia coli-Derived 6-Deoxyerythronolide B
Recently, the feasibility of using Escherichia coli for the heterologous biosynthesis of complex polyketides has been demonstrated. In this report, the development of a robust high-cell-density fed-batch procedure for the efficient production of complex polyketides is described. The effects of vario...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126764/ https://ncbi.nlm.nih.gov/pubmed/12089005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.7.3287-3292.2002 |
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