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Biosynthesis of Polyketides in Heterologous Hosts

Polyketide natural products show great promise as medicinal agents. Typically the products of microbial secondary biosynthesis, polyketides are synthesized by an evolutionarily related but architecturally diverse family of multifunctional enzymes called polyketide synthases. A principal limitation f...

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Detalles Bibliográficos
Main Authors: Pfeifer, Blaine A., Khosla, Chaitan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC99020/
https://ncbi.nlm.nih.gov/pubmed/11238987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.65.1.106-118.2001
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