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Lipid Synthetic Transcription Factor SREBP-1a Activates p21(WAF1/CIP1), a Universal Cyclin-Dependent Kinase Inhibitor
Sterol regulatory element-binding proteins (SREBPs) are membrane-bound transcription factors that regulate lipid synthetic genes. In contrast to SREBP-2, which regulates cellular cholesterol level in normal cells, SREBP-1a is highly expressed in actively growing cells and activates entire programs o...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1265776/ https://ncbi.nlm.nih.gov/pubmed/16199872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.20.8938-8947.2005 |
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