Lipid Synthetic Transcription Factor SREBP-1a Activates p21(WAF1/CIP1), a Universal Cyclin-Dependent Kinase Inhibitor

Sterol regulatory element-binding proteins (SREBPs) are membrane-bound transcription factors that regulate lipid synthetic genes. In contrast to SREBP-2, which regulates cellular cholesterol level in normal cells, SREBP-1a is highly expressed in actively growing cells and activates entire programs o...

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Autors principals: Inoue, Noriyuki, Shimano, Hitoshi, Nakakuki, Masanori, Matsuzaka, Takashi, Nakagawa, Yoshimi, Yamamoto, Takashi, Sato, Ryuichiro, Takahashi, Akimitsu, Sone, Hirohito, Yahagi, Naoya, Suzuki, Hiroaki, Toyoshima, Hideo, Yamada, Nobuhiro
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265776/
https://ncbi.nlm.nih.gov/pubmed/16199872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.20.8938-8947.2005
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