Suppression of the Pancreatic Duodenal Homeodomain Transcription Factor-1 (Pdx-1) Promoter by Sterol Regulatory Element-binding Protein-1c (SREBP-1c)

Overexpression of sterol regulatory element-binding protein-1c (SREBP-1c) in β cells causes impaired insulin secretion and β cell dysfunction associated with diminished pancreatic duodenal homeodomain transcription factor-1 (PDX-1) expression in vitro and in vivo. To identify the molecular mechanism...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Amemiya-Kudo, Michiyo, Oka, Junko, Takeuchi, Yoshinori, Okazaki, Hiroaki, Yamamoto, Takashi, Yahagi, Naoya, Matsuzaka, Kaori, Okazaki, Sachiko, Osuga, Jun-ichi, Yamada, Nobuhiro, Murase, Toshio, Shimano, Hitoshi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Gene Regulation
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151036/
https://ncbi.nlm.nih.gov/pubmed/21652712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.186221
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