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Genome Architecture of the Human β-Globin Locus Affects Developmental Regulation of Gene Expression
To test the role of gene order in globin gene expression, mutant human β-globin locus yeast artificial chromosome constructs were used, each having one additional globin gene encoding a “marked” transcript (ɛ(m), γ(m), or β(m)) integrated at different locations within the locus. When a β(m)-globin g...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1265765/ https://ncbi.nlm.nih.gov/pubmed/16199858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.20.8765-8778.2005 |
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