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The basis for TCR-mediated regulation of the IL-2 receptor α chain gene: role of widely separated regulatory elements
The interleukin-2 receptor α (IL-2Rα) chain is a component of high-affinity IL-2 receptors and thus is a key regulator of lymphocyte proliferation. Lineage-restricted and activation-dependent IL-2Rα transcription is controlled by four upstream positive regulatory regions (PRRs) and one downstream PR...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126074/ https://ncbi.nlm.nih.gov/pubmed/12065418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf321 |
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