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IL-2 negatively regulates IL-7 receptor α chain expression in activated T lymphocytes
Interleukin (IL)-2 is a type I four-α-helical bundle cytokine that plays vital roles in antigen-mediated proliferation of peripheral blood T cells and also is critical for activation-induced cell death. We now demonstrate that IL-2 potently decreases expression of IL-7 receptor α chain (IL-7Rα) mRNA...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129770/ https://ncbi.nlm.nih.gov/pubmed/12354940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212214999 |
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