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Involvement of human polynucleotide kinase in double-strand break repair by non-homologousend joining
The efficient repair of double-strand breaks (DSBs) in DNA is critical for the maintenance of genome stability. In mammalian cells, repair can occur by homologous recombination or by non-homologous end joining (NHEJ). DNA breaks caused by reactive oxygen or ionizing radiation often contain non- conv...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126026/ https://ncbi.nlm.nih.gov/pubmed/12032095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.11.2827 |
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