ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair

The cellular response to double-strand breaks (DSBs) in DNA is a complex signalling network, mobilized by the nuclear protein kinase ataxia-telangiectasia mutated (ATM), which phosphorylates many factors in the various branches of this network. A main question is how ATM regulates DSB repair. Here,...

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Detaylı Bibliyografya
Asıl Yazarlar: Segal-Raz, Hava, Mass, Gilad, Baranes-Bachar, Keren, Lerenthal, Yaniv, Wang, Shih-Ya, Chung, Young Min, Ziv-Lehrman, Shelly, Ström, Cecilia E, Helleday, Thomas, Hu, Mickey C.-T., Chen, David J, Shiloh, Yosef
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2011
Konular:
Scientific Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128972/
https://ncbi.nlm.nih.gov/pubmed/21637298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.96
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