ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair

The cellular response to double-strand breaks (DSBs) in DNA is a complex signalling network, mobilized by the nuclear protein kinase ataxia-telangiectasia mutated (ATM), which phosphorylates many factors in the various branches of this network. A main question is how ATM regulates DSB repair. Here,...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Segal-Raz, Hava, Mass, Gilad, Baranes-Bachar, Keren, Lerenthal, Yaniv, Wang, Shih-Ya, Chung, Young Min, Ziv-Lehrman, Shelly, Ström, Cecilia E, Helleday, Thomas, Hu, Mickey C.-T., Chen, David J, Shiloh, Yosef
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2011
Assuntos:
Scientific Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128972/
https://ncbi.nlm.nih.gov/pubmed/21637298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.96
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares