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A polytopic membrane protein displays a reversible topology dependent on membrane lipid composition
To address the role of phospholipids in the topological organization of polytopic membrane proteins, the function and assembly of lactose permease (LacY) was studied in mutants of Escherichia coli lacking phosphatidylethanolamine (PE). PE is required for the proper conformation and active transport...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125992/ https://ncbi.nlm.nih.gov/pubmed/11980707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.9.2107 |
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