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Topology of polytopic membrane protein subdomains is dictated by membrane phospholipid composition

In Escherichia coli, the major cytoplasmic domain (C6) of the polytopic membrane protein lactose permease (LacY) is exposed to the opposite side of the membrane from a neighboring periplasmic domain (P7). However, these domains are both exposed on the periplasmic side of the membrane in a mutant of...

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Autores principales: Wang, Xiaoyuan, Bogdanov, Mikhail, Dowhan, William
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC131068/
https://ncbi.nlm.nih.gov/pubmed/12411485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf571
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