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In vitro reconstitution of lipid-dependent dual topology and postassembly topological switching of a membrane protein

Phospholipids could exert their effect on membrane protein topology either directly by interacting with topogenic signals of newly inserted proteins or indirectly by influencing the protein assembly machinery. In vivo lactose permease (LacY) of Escherichia coli displays a mixture of topological conf...

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Autores principales: Vitrac, Heidi, Bogdanov, Mikhail, Dowhan, William
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677496/
https://ncbi.nlm.nih.gov/pubmed/23690595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304375110
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