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Effects of mixed proximal and distal topogenic signals on the topological sensitivity of a membrane protein to the lipid environment

The final topology of membrane proteins is thought to be dictated primarily by the encoding sequence. However, according to the Charge Balance Rule the topogenic signals within nascent membrane proteins are interpreted in agreement with the Positive Inside Rule as influenced by the protein phospholi...

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Pubblicato in:Biochim Biophys Acta
Autori principali: Vitrac, Heidi, Dowhan, William, Bogdanov, Mikhail
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660859/
https://ncbi.nlm.nih.gov/pubmed/28432030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2017.04.010
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