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To flip or not to flip: lipid–protein charge interactions are a determinant of final membrane protein topology

The molecular details of how lipids influence final topological organization of membrane proteins are not well understood. Here, we present evidence that final topology is influenced by lipid–protein interactions most likely outside of the translocon. The N-terminal half of Escherichia coli lactose...

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Detalhes bibliográficos
Main Authors: Bogdanov, Mikhail, Xie, Jun, Heacock, Phil, Dowhan, William
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528571/
https://ncbi.nlm.nih.gov/pubmed/18779371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200803097
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