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Lipid-Protein Interactions Drive Membrane Protein Topogenesis in Accordance with the Positive Inside Rule

Transmembrane domain orientation within some membrane proteins is dependent on membrane lipid composition. Initial orientation occurs within the translocon, but final orientation is determined after membrane insertion by interactions within the protein and between lipid headgroups and protein extram...

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Bibliografiska uppgifter
Huvudupphovsmän: Bogdanov, Mikhail, Xie, Jun, Dowhan, William
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665083/
https://ncbi.nlm.nih.gov/pubmed/19074771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R800081200
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