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Lipid-Protein Interactions Drive Membrane Protein Topogenesis in Accordance with the Positive Inside Rule

Transmembrane domain orientation within some membrane proteins is dependent on membrane lipid composition. Initial orientation occurs within the translocon, but final orientation is determined after membrane insertion by interactions within the protein and between lipid headgroups and protein extram...

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Detalhes bibliográficos
Main Authors: Bogdanov, Mikhail, Xie, Jun, Dowhan, William
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665083/
https://ncbi.nlm.nih.gov/pubmed/19074771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R800081200
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