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To flip or not to flip: lipid–protein charge interactions are a determinant of final membrane protein topology

The molecular details of how lipids influence final topological organization of membrane proteins are not well understood. Here, we present evidence that final topology is influenced by lipid–protein interactions most likely outside of the translocon. The N-terminal half of Escherichia coli lactose...

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Autori principali: Bogdanov, Mikhail, Xie, Jun, Heacock, Phil, Dowhan, William
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528571/
https://ncbi.nlm.nih.gov/pubmed/18779371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200803097
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